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SomaFocus

High-resolution electrophysiological readouts from inside intact 3D cultures

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Live Circuit Readouts from Deep Inside Intact Brain Organoids

SomaFocus captures live circuit-level activity from within the full volume of brain organoids and other electrically active 3D cultures to reveal how neurons interact, communicate, and form circuits.

Make the Most of your 3D Model
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Disease Model Discovery

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Therapeutic Screening & Drug Development

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Assess Electrophysiological Function via Circuit Analysis

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Eliminate Extensive and Complicated Prep

Simply take an organoid from media, place it into our environmentally controlled platform and start recording instantly inside intact organoids. SomaFocus reveals the real-time functional dynamics of networks inside 3D tissues—not just their structure or molecular makeup.

Real-Time Data Capture and Visualization

Instantly view spiking activity, circuit synchrony, and network-level dynamics from inside organoids as recordings happen. Visualize connectivity maps, oscillations, and excitatory/inhibitory balance across the full 3D volume.

Bridge the gap between in-vitro experimentation and clinically relevant human neuroscience
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WHAT SCIENTISTS ARE SAYING:
I'm genuinely blown away by the SomaFocus system. We've tested several MEA platforms over the years and were never able to generate meaningful data from our organoid models, until now. SomaFocus has completely changed the game for us.
Andrea Rossi, PhD, Group Leader - Environmental Adaptation & Cellular ResilienceLabHead - Genome Engineering & Model Development Core Unit IUF-Leibniz Institute
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