Janus Probe
Doubling Recording Density
With microelectrodes on both sides of the probe shanks, DBC's new Janus probe can record from neurons hidden from traditional single-sided probes. These "blind spots" will always exist for a single-sided probe, regardless of channel count. Take another dive into the same brain region with the Janus probe and re-discover the underlying neural circuits with hidden single-units revealed.
Two Sides powerful.
The JANUS Probe
Delivers Results:
Key Publication
NEUROSCIENCE
Selection of experience for memory by hippocampal sharp wave ripples
Wannan Yang, Chen Sun, Roman Huszár, Thomas Hainmueller, Kirill Kiselev, György Buzsáki
Abstract
The authors have described their work and analysis here: https://winnieyangwannan.github.io/RippleTagging/
"Being able to record from large numbers of neurons simultaneously was really crucial for our study. Dual side probe from Diagnostic Biochips was really the key for collecting the high quality data used in this study."
Winnie Yang, NYU Neuroscience Institute & New York University, Langone Medical Center
Single-units from CA1 Cell Layer Recorded from Both Sides of the Probe Shanks
Isolated pyramidal cells (triangles) and interneurons (circles) from microelectrodes (squares) on both front (red) and back (blue) sides of probe shanks.
A Symphony from the Hippocampus
A symphony orchestrated by 422 pyramidal cells from CA1 of a mouse recorded during a spatial navigation task. Each cell corresponds to a specific note of a particular instrument.
Can you spot place cell sequences during exploration and two ripples while the animal is at rest?
Courtesy of the Buzsáki lab
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