Skip to content

Our Story

Diagnostic Biochips’ mission is to provide Intuitive and powerful neural probes designed to enable groundbreaking research in electrophysiology, and cloud-based software for spike sorting and analysis – anywhere, anytime.

Our Team

Rect_Leelab-400x250
Rect_Dylanmicroscope-400x250
Rect_FanBrian-400x250

How We Started

Diagnostic Biochips was launched on the premise that users are ready for a turnkey multichannel extracellular recording system on par with laboratory assays and instruments found in other fields such as genetics. The foundational probe technology is based on Brian Jamieson and Fan Wu’s doctoral work at the University of Michigan, with several years of development funded in cooperation with the Howard Hughes Medical Institute/JFRC (2007-2016). We are located in Glen Burnie, Maryland (near BWI airport), which we half-jokingly describe as the emerging neurotech capital of the world.

Rect_FanBrianLee-600x594

Our Leadership

Team-Brian-400x396

Brian Jamieson

Founder & CEO

Brian Jamieson founded Diagnostic Biochips (DBC) in 2013 to drive groundbreaking advances in understanding the brain through the development of advanced neural interfacing systems.

Team-Fan-400x396

Fan Wu

CTO & VP Product Development

Fan Wu is a biomedical and electrical engineer with more than 10 years of experience in design, micro-fabrication and testing of micro-electromechanical systems (MEMS) for biomedical applications.

Our Progress at a Glance

Rect_waferlab-600x375

Formation

Diagnostic Biochips emerged from engineering services company Scientific & Biomedical Microsystems (SBM) in 2013 to commercialize technology developed under contract with the Howard Hughes Medical Institute’s Janelia Research Campus. With over $6M of R&D funding from the NIH and DARPA, Diagnostic Biochips has been expanding our preclinical neurosensor’s capabilities.

Rect_workingatmicro-600x375

Building Momentum

A lack of appropriately scaled and widely applicable tools to study structures at the neural network level was identified as one of the barriers to allowing scientists to develop a detailed, functional description of the brain. In 2014, a consortium of federal agencies including the NIH, NSF, DARPA, the FDA, reached the same conclusion. As a result, The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, a multi-decadal, multi-billion dollar program, was launched to accelerate the understanding of the brain, and advance therapies and cures for the growing burden of brain disease. We are proud to be aligned.

Rect_wiringcloseup-600x375

Current Focus

By accelerating the development and application of innovative technologies, researchers will be able to produce a revolutionary new picture of the brain that, for the first time, shows how individual cells and complex neural circuits interact in both time and space. Long desired by researchers seeking new ways to treat, cure and even prevent brain disorders, this picture will fill major gaps in our current knowledge and provide unprecedented opportunities for exploring exactly how the brain enables the human body to record, process, utilize, store and retrieve vast quantities of information, all at the speed of thought.

Company Progression Timeline

Dec 2003
Oct 2012
May 2013
Jun 2013
Jul 2013
Oct 2014
Nov 2014
Oct 2015
Dec 2015
Oct 2016
Dec 2016
Oct 2017
Oct 2017
Oct 2018
Oct 2019
Oct 2019
Oct 2019
Dec 2019
Jan 2020
Jan 2021
Feb 2021
Oct 2021
Oct 2021
Dec 2021
Dec 2021
Dec 2021
Jan 2022
2003: Brian Jamieson defends thesis on active neural probes

2003: Brian Jamieson defends thesis on active neural probes

Brian Jamieson defends thesis on active neural probes

2012: DBC Incorporated

2012: DBC Incorporated

DBC Incorporated

2013: SBIR grant from NIAAA to measure interaction of ethanol with neuronal circuits

2013: SBIR grant from NIAAA to measure interaction of ethanol with neuronal circuits

SBIR grant from NIAAA: SBIR grant from NIAAA to measure interaction of ethanol with neuronal circuits

2013: SBIR Grant from NIDA: effect of drug abuse on brain circuitry

2013: SBIR Grant from NIDA: effect of drug abuse on brain circuitry

SBIR grant from NIAAA: SBIR Grant from NIDA: effect of drug abuse on brain circuitry

2013: Distribution agreement with Cambridge Neurotech and sale of first product

2013: Distribution agreement with Cambridge Neurotech and sale of first product

Distribution agreement with Cambridge Neurotech and sale of first product

2014: SBIR grant from NHLBI: continuous measurement of chemotherapeutic drugs

2014: SBIR grant from NHLBI: continuous measurement of chemotherapeutic drugs

SBIR grant from NHLBI: continuous measurement of chemotherapeutic drugs

2014: Fan Wu defends thesis on optogenetics probes

2014: Fan Wu defends thesis on optogenetics probes

Fan Wu defends thesis on optogenetics probes

2015: SBIR grant (Brain Initiative) from NIMH for continuous psychiatric drug monitoring

2015: SBIR grant (Brain Initiative) from NIMH for continuous psychiatric drug monitoring

SBIR grant (Brain Initiative) from NIMH for continuous psychiatric drug monitoring

2015: License and Distribution Agreement with Howard Hughes Medical Institute

2015: License and Distribution Agreement with Howard Hughes Medical Institute

License and Distribution Agreement with Howard Hughes Medical Institute

2016: Review paper on Point of care technology in IEEE Journal of Translational Research in Health and Medicine

2016: Review paper on Point of care technology in IEEE Journal of Translational Research in Health and Medicine

Review paper on Point of care technology in IEEE Journal of Translational Research in Health and Medicine

2016: VP of New Product Development Fan Wu, Ph.D. joins company

2016: VP of New Product Development Fan Wu, Ph.D. joins company

VP of New Product Development Fan Wu, Ph.D. joins company

2017: DARPA grant for continuous measurement of cytokines

2017: DARPA grant for continuous measurement of cytokines

DARPA grant for continuous measurement of cytokines

2017: Chemosensing Technology Featured in Journal of Materials Chemistry

2017: Chemosensing Technology Featured in Journal of Materials Chemistry

Chemosensing Technology Featured in Journal of Materials Chemistry

2018: US Patent issued: In Vivo Biosensor

2018: US Patent issued: In Vivo Biosensor

US Patent issued: In Vivo Biosensor

2019: US Patent issued: Optical Neural probe

2019: US Patent issued: Optical Neural probe

US Patent issued: Optical Neural probe

2019: Probe Technology Featured in Frontiers in Neuroscience

2019: Probe Technology Featured in Frontiers in Neuroscience

Probe Technology Featured in Frontiers in Neuroscience

2019: Review Paper Authored on Continuous Monitoring in Translational Research

2019: Review Paper Authored on Continuous Monitoring in Translational Research

Review Paper Authored on Continuous Monitoring in Translational Research

2019: CEO Greg Alden joins company

2019: CEO Greg Alden joins company

CEO Greg Alden joins company

2020: Probe User Michael Long Featured on cover of Cell for Work Using DBC probe

2020: Probe User Michael Long Featured on cover of Cell for Work Using DBC probe

Probe User Michael Long Featured on cover of Cell for Work Using DBC probe

2021: VP of Marketing Nancy Palmer joins company

2021: VP of Marketing Nancy Palmer joins company

VP of Marketing Nancy Palmer joins company

2021: VP of Sales, Scott Smith, Ph.D. joins company

2021: VP of Sales, Scott Smith, Ph.D. joins company

VP of Sales, Scott Smith, Ph.D. joins company

2021: Series A Financing Completed

2021: Series A Financing Completed

Series A Financing completed

2021: Integrated 64 and 128 Probe Product Released

2021: Integrated 64 and 128 Probe Product Released

Integrated 64 and 128 Probe Product Released

2021: Deep Array product released (?) Beta Rlease (?)

2021: Deep Array product released (?) Beta Rlease (?)

Deep Array product released (?) Beta Rlease (?)

2021: Deep Array probe introduced

2021: Deep Array probe introduced

Deep Array probe introduced, enabling high density, single unit recording in awake and behaving non-human primates, including in deep structures.

2021: Dual-sided Janus probe introduced

2021: Dual-sided Janus probe introduced

2021: Dual-sided Janus probe introduced, recording from cells in a complete 360 degree diameter line of sight around probe.

2022: New Cloud-based Software coming in 2022

2022: New Cloud-based Software coming in 2022

2022: New Cloud-based Software coming in 2022.